Harvard Update on Severe Asthma 2025

Program Overview & Key Updates

• Welcome and introduction to the online audience
• Update on Severe Asthma 2025: key changes and takeaways
• Current state of severe asthma investigation and care
• Multidisciplinary approach to severe asthma management
• Adult and pediatric severe asthma considerations
• Practical strategies for complex clinical decision-making

Disease Biology, Genetics & Phenotypes

• Asthma genetics and the environment in severe asthma
• Molecular sub-phenotypes in asthma
• Eosinophilic lung disease and overlap with asthma
• Allergic bronchopulmonary aspergillosis and eosinophilic airway disease
• Insights from the Severe Asthma Research Program
• Pathophysiologic insights from novel imaging techniques
• What distinguishes asthmatic versus non-asthmatic allergic airway responses

Diagnosis & Assessment

• Diagnostic assessment of severe asthma
• Practical framework for difficult-to-control asthma
• Diagnostic considerations in children with severe asthma
• Drivers of asthma in school-aged children
• Airway oscillometry in adults and very young children
• New recommendations for interpreting pulmonary function tests
• Identifying specific severe asthma phenotypes and endotypes

Environment, Triggers & Exposures

• Indoor environments and asthma exacerbations
• Occupational exposures and severe asthma
• Environmental contributions to severe asthma
• Microbiome and asthma: emerging evidence
• Smoking, COPD, and chronic obstructive asthma
• Asthma-COPD overlap considerations
• Trigger recognition and exposure-focused care planning

Comorbidities, Mimics & Overlap Syndromes

• Gastroesophageal reflux and severe asthma
• Laryngeal disordered breathing mimicking severe asthma
• Upper airway obstruction considerations
• Rhinosinusitis and nasal polyposis treatment
• Obesity, diabetes, and asthma metabolic links
• Asthma mimics such as tracheobronchomalacia
• Recognizing non-asthma causes of persistent respiratory symptoms

Pediatric Severe Asthma

• Managing severe asthma in children
• Diagnostic considerations in children with severe asthma
• Drivers of asthma in school-aged children
• Assessment of difficult-to-control pediatric asthma
• Pediatric phenotypes and treatment considerations
• Family-centered and school-age asthma management strategies

Treatment Strategies & Biologic Therapy

• Choosing among the biologics for severe asthma
• Utilizing novel asthma therapeutics with confidence
• Management of asthma with aspirin-exacerbated respiratory disease
• Anti-inflammatory rescue options and challenges
• Clinical remission in asthma as a goal of guideline-directed therapy
• Recent GINA and NAEPP guideline-based treatment strategies
• Novel therapies and future directions in severe asthma care

Interactive Case-Based Learning

• Interactive case discussions in real-world severe asthma
• Complex diagnostic dilemmas
• Complex therapeutic dilemmas
• Approach to patients who remain uncontrolled despite standard therapy
• Multidisciplinary case discussion and treatment planning
• Practical severe asthma protocol review

It is ideal for pulmonologists, allergists, primary care physicians, specialty physicians, NPs, PAs, medical trainees, researchers, and clinicians involved in severe asthma and respiratory medicine.

The package includes 29 recorded videos and 30 PDF files, with a total size of 6 GB.

The course covers severe asthma assessment, difficult-to-control asthma, phenotypes and endotypes, asthma genetics, environmental triggers, eosinophilic lung disease, ABPA, SARP insights, pediatric severe asthma, oscillometry, pulmonary function testing, occupational asthma, GERD, laryngeal disordered breathing, rhinosinusitis, nasal polyposis, obesity, diabetes, tracheobronchomalacia, smoking, COPD, ACO, biologic therapy selection, AERD, anti-inflammatory rescue, clinical remission, GINA and NAEPP guidelines, and novel therapies.

Yes. The course focuses on diagnostic assessment, phenotype-based care, treatment selection, biologics, comorbidities, mimics, guideline-directed therapy, and real-world case discussions.

No. This course package does not include CME points.

You can contact us at support@getmedicalcourses.com.